Using -OMICs approaches to understand how flow regulates cardiovascular diseases
Our lab studies the mechanisms by which blood flow regulates endothelial biology and dysfunction, which leads to atherosclerosis and aortic valve calcification. In addition to in vitro (a cone-and-plate bioreactor) systems, the lab also developed an in vivo model (a mouse partial carotid ligation model) in conjunction with OMICs approaches to understand how disturbed flow vs. stable flow differently regulate vascular and valve endothelial biology and pathobiology at the genome-, epigenome-, and metabolome-wide level. With these methods, we have been able to carry out several OMICs studies that have allowed us to identify mechanosensitive mRNAs, microRNAs, epigenetic DNA methylome, metabolites, and long non-coding RNAs (on-going work). These genome-, epigenome- and metabolome-wide OMICs studies have guided us not only to identify mechanosensitive genes, metabolites and epigenetic changes, but to demonstrate the critical role that some of these flow-sensitive molecular transducers play a role in controlling endothelial biology, atherosclerosis and aortic valve disease
Currently Recruiting Postdoctoral Fellows
Postdoctoral Fellow in Mechanobiology and Disease at Emory
A postdoctoral position is available immediately to study the mechanisms by which mechano-sensitive genes and epigenetics regulate vascular biology, atherosclerosis and aortic valve disease, and to develop gene-based therapies and targeted delivery methods in Coulter Department of Biomedical Engineering at Emory University in Atlanta, Georgia, USA. We are looking for a motivated and talented biomedical scientist or engineer with PhD or MD in related fields and with strong publication record. Please apply here: https://faculty-emory.icims.com/jobs/18016/job, and also send your CV by e-mail to Professor Jo. Applications will be reviewed on a rolling basis until filled but by June 10, 2018.
Contact
➤ LOCATION
Emory University
1760 Haygood Dr NE,
HSRB Room E-197
Atlanta, GA 30322
☎ CONTACT
Hanjoong Jo, Ph.D.
hanjoong.jo@bme.gatech.edu
Administrative Assistant to Dr. Jo
Colleen Spellen
(404) 712-9136
cspelle@emory.edu






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Visit us during the poster sessions! Here is visiting student Junyao Wang presenting the “Role of miR-744 in Endoth… https://t.co/ERVx1qr0qD
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Visit us during the poster sessions! Here is PhD candidate Joan Fernandez Esmerats presenting his research project… https://t.co/3pN6qcmdAE
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Visit us during the poster sessions! Here is PhD student Darian Williams presenting “The role of KLK10 in Endotheli… https://t.co/VjFgmkMZks
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Visit us during the poster sessions! Here is PhD student Catherine Demos presenting her work: “Bone Morphogenic Pro… https://t.co/0ki9eGmBaZ
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Visit us during the poster sessions! Here is Dr. Sandeep Kumar presenting his poster titled “Accelerated atheroscle… https://t.co/he3QGg3TWq
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The 13th International Symposium on Biomechanics in Vascular Biology and CVD is officially under way! https://t.co/dvBPDzImxO
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RT @BME_GT_Emory: Biomedical Engineering Ranked #2 in U.S. News Graduate Rankings for 2019. https://t.co/Wr0UcZVwZ5 https://t.co/RuXXgvRFH5
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Welcoming in a new cohort of accepted students. We’re so excited you’re joining us for Grad Recruitment!… https://t.co/QL49Mu8HNC
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RT @American_Heart: Twitter chat on all things valve disease starts in ONE HOUR. Join us! #ValveDiseaseDay https://t.co/UK2yCK9UoN
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Congratulations to Joan Fernandez on the BME Seminar Best Presentation Award! (and Happy Birthday!)